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Background

Nail Clubbing: A Potential Sign of Lung Cancer

Background

What is Nail Clubbing?

Nail clubbing occurs when nails appear wider, spongelike, or swollen resembling an upside-down spoon. It often indicates an underlying health condition.

Finger Clubbing and Lung Cancer

Finger clubbing, characterized by swelling of the fingertips and changes in nail appearance, is a common symptom of lung cancer. In adults, lung malignancy is the most prevalent pulmonary cause of clubbing, affecting approximately 5-15% of patients.

Causes of Nail Clubbing in Lung Cancer

Research and Hypotheses

While the exact cause of nail clubbing in lung cancer is still under investigation, experts suspect that increased vascular endothelial growth factor (VEGF) may play a role. However, further research is needed to fully establish the cause.


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